I run very frequently with the Deuter Race X Air. I love this pack, mesh everywhere that touches my body, and a frame that holds the back away from my body. Plus straps that stabilize well when running. I have done many 10+ mile runs with this pack, carrying spare clothes, water, and food for long trail runs around Boulder. Plus I use the pack for running to do errands around town, getting some exercise while I do errands. The Race X Air is on the small side, so you can't carry too much, but that means it does not flop around when near empty too.
link:[Racer [Racer X Air](http://www.deuter.com/en_US/backpack-details.php?category=123&artnr=32039 "Racer X Air")